Each egg contained an oncosphere
that hatched and activated in small intestine.
A double etiopathogenic mechanism is possible, with the primitive blood-graft of oncosphere
or hexcanth and a graft in the pelvic pouch of Douglas of protoscolices coming from the cracking of abdominal hydatid cysts.
The egg hatches in the intestinal tract and the oncosphere
is freed migrates through the intestinal wall and gains access via the circulatory system to the muscles brain and other tissues of the host where it transforms into the metacestode form or cysticercus.
Hydatid disease is a zoonosis caused by the infestation of the oncosphere
(embryo) of Echinococcus Granulosus.
5,8,10) The eggs are round to oval in shape, measure an average of 25-40 [micro]m in diameter, and contain an oncosphere
with 6 hooklets.
multilocularis are sensitive to environmental factors: elevated temperature and desiccation can effectively reduce oncosphere
infectivity (Veit et al.
Induction of protection against porcine cysticercosis by vaccination with recombinant oncosphere
The egg hatches in the small intestine and releases an oncosphere
14) Some cysticercus antigens can react with anti-sera against T solium adult and oncosphere
, indicating that they also have common antigens.
The eggs release the oncosphere
(immature larvae) in the animal's intestine.
Humans are accidental hosts and get infected by ingestion of embiyonated eggs, which then hatches in the small intestine and releases an oncosphere
that moves to the circulatory system by penetrating small intestine wall and gets lodged in different organs, in particular liver and lungs.
Following ingestion by a human or ungulate intermediate host (sheep, goats, pigs, cattle, horses, and camels), an oncosphere
larva is released from the egg.