However, scientists eventually discovered that organic arsenic
could break down into the cancer-causing inorganic arsenic when metabolized by chickens and on exposure to the elements after excretion.
Even though it's organic arsenic
being fed to these chickens, [they contain] a lot more inorganic arsenic at the end of the day," says John F.
Occurrence and stability of inorganic and organic arsenic
species in wines, rice wines, and beers from central European market.
Almost nothing is known regarding health effects of organic arsenic
compounds in humans," says the Agency for Toxic Substances and Disease Registry.
A second organic arsenic
from that broad licensing arrangement, ZIO-102, is expected to undergo further preclinical study this year as ZIO-101 progresses through phase I study in both hematologic and solid tumor cancers.
Due to inorganic arsenic trioxide's severe cardiotoxicity and neurotoxicity profile, darinaparsin, an organic arsenic
, was thought to be a far better treatment candidate and these studies encourage additional preclinical and clinical study, as a single agent and in combination.
4, 2014 /PRNewswire/ -- About Biologic Therapeutics Biologic therapeutics include virus, therapeutic serum, toxin, allergenic product, antitoxin, blood component or derivative, vaccine, blood, protein (except any chemically synthesized polypeptide), or analogous product, or arsphenamine or derivative of arsphenamine (or any other trivalent organic arsenic
compound), intended for the prevention, treatment, or cure of a disease or condition.
Little is known about the relationship of organic arsenic
compounds and humans (ATSDR, 2007).
In brief, differences in interpretation of the association between arsenic and diabetes can be reached based on different methodological approaches used to account for organic arsenic
due to seafood consumption and whether to include urinary creatinine as an adjustment factor in the statistical model.
So people who eat seafood are going to be exposed to very high levels of arsenic, but in this case it's this type of organic arsenic
that is actually nontoxic, so when we do research we need to always be very careful about exposure assessment, and we need to distinguish between inorganic and organic arsenic
Two remaining forms of organic arsenic
found-DMA and MMA-are considered to be possible carcinogens.
At the time roxarsone was approved, scientists believed its organic arsenic
base would be excreted unchanged.