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orphan drug |
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orphan drug, drug developed under the U.S. Orphan Drug Act (1983) to treat a disease that affects fewer than 200,000 people in the United States. The orphan drug law offers tax breaks and a seven-year monopoly on drug sales to induce companies to undertake the development and manufacturing of such drugs, which otherwise might not be profitable because of the small potential market. (Of the 5,000 diseases covered under the act, 47% affect fewer than 25,000 people.) The law has led to the introduction of valuable new drugs for the treatment of rare diseases, but some drug companies have been accused of abusing the law's provisions by making inordinately high profits on orphan drugs under monopoly. Since the 1983 act went into effect, many orphan drugs have been approved, including those for the treatment of such conditions as AIDS AIDS or acquired immunodeficiency syndrome, fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. ..... Click the link for more information. , cystic fibrosis cystic fibrosis (sĭs`tĭk fībrō`sĭs) ..... Click the link for more information. , blepharospasm (uncontrolled rapid blinking), and snake bite. orphan drug [¦ȯr·fən ′drəg] (pharmacology) A pharmaceutical developed to treat a disease that afflicts relatively few people. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Receiving EMEA orphan drug designation for decitabine may accelerate the approval process in Europe by allowing us to combine the results of our Phase III program in the United States with previous European studies that have produced positive results," said Dr. gained 13 percent Tuesday after the company announced that its Apomate drug had received orphan drug status from the U. Avonex is protected from competition by "me-too" medications until 2003 under the federal Orphan Drug Act. |
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