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A bone-forming cell of mesenchymal origin.



a cell that is involved in bone formation in vertebrate animals and man. Osteoblasts arise during the ossification of skeletal rudiments. In mature bone, they are found only in regions of injury, regeneration, and remodelling. They also take part in the formation and calcification of the intercellular substance of a bone.

References in periodicals archive ?
In vitro assays showed that LPNS promoted the differentiation of bone marrow mesenchymal stem cells and mononuclear cells into osteoblasts and osteoclasts, respectively, but had no effect on osteoclast activation.
OCS inhibit osteoblast maturation, secretion and transformation into osteocytes.
In the present study increase in osteoclast activity was associated with elevation of crosslaps and osteonectin concentration, bone turnover and osteoblasts activity (osteocalcin concentration was also increased in weeks 4 and 8 after operation).
The effects of laser irradiation on osteoblast and osteosarcoma cell proliferation and differentiation in vitro.
To investigate the effect of grooves on osteoblast attachment, Li et al prepared HA discs by pressing the nano HA powder and sintering at 1100oC for 2 h.
Induction of osteoblast differentiation and inhibition of osteoclastogenesis by transduction of MC3T3-E1 cells with Ad-siTNF[alpha]-BMP-2 and different conditioned media
During our investigation, medullar bone diameter and trabecular surface area of the defect region, osteoblast surface area in the defect region, and mineralized bone surface area were histomorphometrically measured.
Alkaline phosphatase is one of the most frequently used biochemical markers of osteoblast activity and differentiation (Risteli and Risteli, 1993; Magnusson et al.
Although the pathological mechanism underlying this process is not known thoroughly, it is known that an imbalance in bone cycle occurs because of the involvement of osteoblast differentiation.
Researchers conclude that Peptan(TM) may restore bone density in simulated post-menopausal osteoporosis by stimulating osteoblast growth and differentiation.