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osteopetrosis |
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osteopetrosis [¦äs·tē·ō·pə′rō·səs] (medicine) A rare developmental error of unknown cause but of familial tendency, characterized chiefly by excessive radiographic density of most or all of the bones. Also known as marble bone disease. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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InterMune currently markets ACTIMMUNE(R) (Interferon gamma-1b) Injection in the United States for the treatment of chronic granulomatous disease (CGD) and severe, malignant osteopetrosis and is in Phase III clinical trials for the treatment of idiopathic pulmonary fibrosis (IPF) and multidrug-resistant tuberculosis (MDR TB). Stem Cell Transplantation in Children with Infantile Osteopetrosis Is Associated with a High Incidence of VOD, Which Could Be Prevented with Defibrotide. Severe, malignant osteopetrosis is a life-threatening congenital disorder in which an overgrowth of bony structures leads to blindness, deafness and increased susceptibility to infection. |
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