is an autosomal dominant disorder characterized by small round or ovoid radio-opacities appearing in the juxta-articular regions of bone.
Epidemiological, clinical and radiological aspects of osteopoikilosis.
Mungovan JA, Tung GA, Lambiase RE, Noto RB, Davis RP Tc-99m MDP Uptake in osteopoikilosis.
(OPK) is a benign rare disorder of the endochondral bone, characterized by small multiple osteocondensation lesions, maximum 10 mm, usually found in the long bones of the limbs, hand, foot, pelvis and spine.
(also called spotted bone) is a benign, possibly autosomal dominant dysplasia of bones, occurring in 1 per 50,000 people.
Rarely, multiple lesions are noted, a condition known as osteopoikilosis
Increased bone density without modifcation of bone shape Osteopetrosis precocious type Generalised AR delayed type Type 1 uniform AD intermediate type Type 2 endobones with renal tubular Generalised AR AR acidosis Similar other types Axial osteosclerosis osteomesopyknosis Focal sclerosis AD AR with bamboo hair in vertebrae/pelvis Pycnodysostosis Generalised AR Osteosclerosis Cortical AD Stanesu type thickening of long bones, defcient facial sinus development Osteopathia striata Radiodense SP XLD isolated with striations on all cranial sclerosis bones with cranial sclerosis Sponastrime Striated AR dysplasia metaphysis Melorheostosis Flowing SP hyperostosis Osteopoikilosis
Radiodense spots AD Mixed sclerosing Combined pattern SP bone dysplasia 2.
Thought to develop in childhood and progress until the closure of the growth plates, osteopoikilosis
is characteristically asymptomatic; however, approximately 15%-20% of patients who suffer from this condition experience mild articular pain and have a joint effusion.
(osteopathia condensans disseminate, spotted bone; OPK) is an asymptomatic, rare bone dysplasia.
(osteopathia condensans disseminata) is a rare sclerosing bone dysplasia of unknown etiology.
It may occur in association with other types of sclerosing bone dysplasias such as osteopoikilosis
and osteopathia striata (4) and with tumor-forming disease such as tuberous sclerosis and neurofibromatosis.
The radiological differential diagnosis include osteopoikilosis
, osteopetrosis, arthrogryposis multiplex congenita, and osteopathia striata (11).