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ouabain

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.02 sec.
ouabain: see digitalis digitalis , any of several chemically similar drugs used primarily to increase the force and rate of heart contractions, especially in damaged heart muscle. The effects of the drug were known as early as 1500 B.C.
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ouabain [wä′bī·ən]
(organic chemistry)
C29H44O12·8H2O White crystals that melt with decomposition at 190°C, soluble in water and ethanol; used in medicine.


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On the day before ouabain selection, stock cultures of A549, C-ter3, and pSup control cells were trypsinized and pooled, and 2  107 cells from each cell line were reseeded at a density of 1  106 cells per 100-mm plate in DMEMF12 medium supplemented with 10% FCS and antibiotics.
In order to find out if hyperpolarization was functionally required for differentiation, the scientists depolarized the hMSCs by exposing them either to high levels of extracellular potassium ions or to ouabain, a compound that blocks the transfer of ions in and out of cells.
gov/) and ouabain loci in mammalian cells have been shown to be either inactive or weakly active (Jaurand 1996).
 
 
 
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