DENVER, July 9, 2015 /PRNewswire/ -- The Colorado Center for Reproductive Medicine (CCRM) is looking for women under the age of 40 with primary ovarian insufficiency
for a research study on in vitro follicle activation (IVA).
MUNICH -- A working group of the European Society of Human Reproduction and Embryology drafted the first international guidelines for managing premature ovarian insufficiency
Fragile X-associated disorders such as primary ovarian insufficiency
and ataxia are similarly identified.
They also cover pathology, including omics for oocyte selection, alterations in gene expression, transgenerational risks by exposure in utero, obesity and oocyte quality, the safety of ovarian stimulation, epigenetics, and the genetic basis for primary ovarian insufficiency
, and technology and clinical medicine, with discussion of polar body screening for aneuploidy and transplantation of ovarian tissue or immature oocytes to preserve and restore fertility.
Once this diagnosis has been excluded, the most common endocrine causes of secondary amenorrhea include polycystic ovary syndrome (PCOS) [evaluated by serum testosterone and/or dehydroepiandrosterone sulfate (DHEAS), ovarian ultrasound, and clinical features such as hirsutism], hypothalamic dysfunction (evaluated by FSH measurement), thyroid disease (evaluated by measurement of TSH and thyroid autoantibodies), hyperprolactinemia (evaluated by measurement of prolactin), or primary ovarian insufficiency
(POI) (evaluated by assessment of estrogen status and measurement of prolactin, FSH, TSH) (1) (Fig.
Around 1% of women suffer from Primary Ovarian Insufficiency
which brings on the menopause at a very young age.
Doctors at the St Marianna University School of Medicine in Kawasaki, Japan, collected viable eggs from women with a condition called primary ovarian insufficiency
Primary ovarian insufficiency
or premature ovarian failure (POI/POF) is one the causes of female infertility.
The link between ovulation and the immune system isn't unexpected; some women with primary ovarian insufficiency
, who undergo an unusually early menopause, have an autoimmune disease of the ovaries.
The mice developed a disorder resembling primary ovarian insufficiency
(POI), a menopause-like condition that affects women under the age of 40, sometimes years or even decades before normal menopause.
Menstrual irregularity can have many causes, including too much exercise, emotional stress, eating too few calories, radiation or chemotherapy, androgen excess, and medical conditions like hyperprolactinemia and primary ovarian insufficiency
Efforts would also be made towards establishing the proof-of-principles for cell based therapy to treat reproductive disorders such as ovarian insufficiency