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oxysterol

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oxysterol [‚äk·sē′stir‚ȯl]
(biochemistry)
Oxidized derivative of cholesterol.
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Arenas notes that the formation of dopamine-producing neurons during brain development in mice is dependent on the activation of a specific receptor in the brain by an oxidised form of cholesterol called oxysterol.
Cholesterol crucial to brain development by Asian News International
The alternative pathway for BA synthesis produces mainly CDCA and requires the enzyme oxysterol 7[alpha]-hydroxylase (CYP7B1) rather than CYP7A1.
Clinical utility of bile acid sequestrants in the treatment of ... by Insull, William, Jr. / Southern Medical Journal
4) The oxysterol liver X receptor (LXR) plays a major role in the regulation of cholesterol homeostasis, stimulating hepatic bile acid synthesis, modulating intestinal cholesterol absorption, and enhancing the expression of many of the genes involved in reverse cholesterol transport.
Colesevelam HCl decreases atherosclerosis and may activate reverse ... by Davidson, Michael H.; Dittakavi, Vani; Bandari, Armin; Davidson, David J.; Maki, Kevin C.; Subbaiah, / Journal of Applied Research
 
 
 
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