taxol

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Related to paclitaxel: Carboplatin

taxol

[′tak‚sōl]
(pharmacology)
C47H51NO14 An alkaloid derived from the Pacific yew tree (Taxus brevifolia) that is used in the treatment of ovarian and breast cancer.
References in periodicals archive ?
The study is a randomised Phase II trial of weekly paclitaxel versus weekly paclitaxel with REOLYSIN in patients with persistent or recurrent ovarian, fallopian tube, or primary peritoneal cancer.
National Cancer Institute (NCI), the combination of REOLYSIN(R) and paclitaxel was uniformly synergistic against six non-small cell lung cancer cell lines examined, including cell lines resistant to paclitaxel or REOLYSIN(R).
and his colleagues became interested in paclitaxel, marketed as Taxol, because previous experiments had indicated that the drug could stabilize microtubules--tiny conveyor belts in cells that normally help them function.
Angela Hoffman, an associate professor of chemistry and physics at the University of Portland in Oregon--a state where hazelnut trees are grown in orchards--says certain varieties of the hazelnut tree produce as much as one-tenth of the paclitaxel found in the Pacific yew tree.
Nowadays, paclitaxel injection has been widely used to cure cancers like non-small cell lung cancer, breast cancer, and ovarian cancer, etc.
In contrast, 12 percent of stents coated with a low dose of the drug and just 4 percent of stents with high-dose paclitaxel were blocked to this degree.
The agreement adds to existing arrangements between the two companies providing for the sale by Faulding of Anzatax(TM) brand paclitaxel throughout Australia, Asia, South Africa, the Middle East and Latin America.
BULK PACLITAXEL MCP-1208 A GLOBAL STRATEGIC BUSINESS REPORT
Patients that were eligible received placebo or Micellar Paclitaxel at one of two different doses (25 mg/m2 and 50 mg/m2) - the same dosing schedule that was used in the company's successful Phase 1/2 clinical study using Micellar Paclitaxel to treat patients with secondary progressive multiple sclerosis.
Previous, smaller studies had indicated that paclitaxel therapy is beneficial.
The use of albumin enables more of the active drug to enter the tumor, and eliminates the need for solvents and the associated toxicities with solvent-based paclitaxel chemotherapy.
In both studies, the Topical Paclitaxel Gel was demonstrated to be safe and well-tolerated when applied once or twice daily to either normal or psoriatic skin.