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pancytopenia

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.03 sec.
pancytopenia [‚pan·sīd·ə′pē·nē·ə]
(medicine)
Abnormally low numbers of all formed elements in the blood.


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Patients with CLL also may develop enlargement of the spleen and lymph nodes, and pancytopenia (depletion of red and white blood cells and platelets), ultimately resulting in hemorrhage, infection and death.
Diagnostic Features: Pancytopenia, oval macrocytes,and hypersegmented neutrophils; megaloblastic hyperplasia; achlorhydria; anti-intrinsic factor antibodies; absent position and vibration sensations; impaired vitamin B12 absorption corrected by intrinsic factor (abnormal Schilling test) =>Folate deficiency +Mechnisms: Delayed DNA replication +Diagnostic Features: Pancytopenia, oval mcrocytes, and hypersegmented neutrophils; megaloblastic hyperplasia.
 
 
 
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