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pantothenic acid |
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pantothenic acid (păn`təthĕn`ĭk): see coenzyme biotin, is a member of the B complex; it was first isolated in 1935 from dried egg yolk, and its structure was established in 1942. Biotin is usually found attached to a lysine residue in certain enzymes, where it participates in reactions involving the transfer of carboxyl ..... Click the link for more information. ; vitamin vitamin, group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes , or they form integral parts ..... Click the link for more information. . pantothenic acidOrganic compound, essential in animal metabolism. The nature of the bound form was clarified through the discovery and synthesis (1947–50) of the compound pantetheine, which contains pantothenic acid combined with the compound thioethanolamine. Pantetheine is part of two larger compounds (coenzyme A and acyl-carrier protein) that promote a large number of metabolic reactions essential for the growth and well-being of animals. A dietary deficiency severe enough to lead to clear-cut disease has not been described in humans; however, when a person is severely malnourished, deficiency of the vitamin appears to contribute to the observed weakness and mental depression. |
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