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penicillamine

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penicillamine [‚penĀ·ə′silĀ·ə‚mēn]
(pharmacology)
C5H11NO2S The most characteristic degradation product of penicillin-type antibiotics; used as a chelating agent, as a drug to reduce cystine excretion in cystinurea, and in the treatment of rheumatoid arthritis.


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They include penicillamine, sulfasalazine and azathioprine.
Aside from DMEP and penicillamine, it is probably the only effective agent that can cross the blood-brain barrier and mobilizes mercury stored in the intracellular space (attached to mitochondria, tubulin, and liposome and in the nucleus of the cell, reversing DNA damage of mercury).
1% (wt/wt) aminoguanidine, pyridoxamine, penicillamine, and nucleophilic compounds NC-I and NC-II.
 
 
 
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