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penicillamine |
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penicillamine [‚pen·ə′sil·ə‚mēn] (pharmacology) C5H11NO2S The most characteristic degradation product of penicillin-type antibiotics; used as a chelating agent, as a drug to reduce cystine excretion in cystinurea, and in the treatment of rheumatoid arthritis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Whether lead elevates homocysteine through enzyme inhibition, as earlier suggested, or conversely, whether homocysteine elevates lead because of intravascular binding [homocysteine has a structure similar to dimercaptosuccinic acid (DMSA) and penicillamine, compounds that are known to bind lead], it is evident that the association exists at very low blood lead levels, and if the former mechanism is operative, supports a biologic effect of lead at low levels. Some of these include the new drug Arava and methotrexate, hydroxychloroquine, penicillamine, and gold injections. penicillamine, procainamide, bleomycin) silica, organic solvents (i. |
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