penicillinase

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Related to penicillinases: cephalosporinase

penicillinase

[‚pen·ə′sil·ə‚nās]
(biochemistry)
A bacterial enzyme that hydrolyzes and inactivates penicillin.
References in periodicals archive ?
This technique, for example, was used successfully to study the extent of variations in penicillinase genes that generate extended-spectrum [beta]-lactamase agents (12).
Both GS553 and GS554 strains, which produced cephalosporinase as well as penicillinase, were resistant to cefotetan, cefmetazole, and cefoxitin as well as piperacillin, cefotaxime, ceftriax-one, cefpodoxime, cefepime, and aztreonam.
Penicillinase synthesis controlled by infectious R Factors in Enterobacteriaceae.

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