pernicious anemia


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Related to pernicious anemia: iron deficiency anemia, aplastic anemia

pernicious anemia:

see anemiaanemia
, condition in which the concentration of hemoglobin in the circulating blood is below normal. Such a condition is caused by a deficient number of erythrocytes (red blood cells), an abnormally low level of hemoglobin in the individual cells, or both these conditions
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pernicious anemia

[pər′nish·əs ə′nēm·ē·ə]
(medicine)
A megaloblastic macrocytic anemia resulting from lack of vitamin B12, secondary to gastric atrophy and loss of intrinsic factor necessary for vitamin B12 absorption, and accompanied by degeneration of the posterior and lateral columns of the spinal cord.
References in periodicals archive ?
12] deficiency is classically caused by pernicious anemia, (3,7) the principal characteristics of which have been reported in detail in several reviews.
Patients suspected to have pernicious anemia may already be on vitamin [B.
12] can prevent pernicious anemia or treat the pernicious anemia once it occurs.
Pernicious anemia may be associated with autoimmune endocrinopathies and antireceptor autoimmune diseases.
Crosby, who authored the preceding article (see page 46) about a woman with pernicious anemia (PA), is a renowned hematologist who, because of his own experience, has changed his method of treating the disease from the traditional needle injection to oral tablets.
Iron deficiency occurs frequently in patients with pernicious anemia.
39) have found that MMA and homocysteine measurements are more sensitive tests of early pernicious anemia and recommend them as better tests.
These are present in the majority (90%) of cases of pernicious anemia but are also present in atrophic gastritis without pernicious anemia[16,17]; however, the absence of these markers does not rule out possible vitamin [B.
Pernicious anemia has its own definition: "A severe anemia caused by the diminution or absence of stomach acid secretion, with consequent failure of the gastric mucosa to secrete the intrinsic factor necessary for the absorption of vitamin [B.
The report also looks at a miscellaneous category that includes cellular immunology and the interaction of the immune system with cellular function as in diabetes, pernicious anemia, and neuroimmune syndromes.