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vaccine
(redirected from pertussis vaccine)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.01 sec.

vaccine

Preparation containing either killed or weakened live microorganisms or their toxins, introduced by mouth, by injection, or by nasal spray to stimulate production of antibodies against an infectious agent. This confers immunity to that agent, since the B lymphocytes remain sensitized to it and respond to later infection by producing more antibodies. The first vaccine, against smallpox, was introduced by Edward Jenner in 1798. Vaccines have been developed against diseases caused by bacteria (e.g., typhoid, whooping cough, tuberculosis) and by viruses (e.g., measles, influenza, rabies, poliomyelitis). Effectiveness varies, and a small percentage of people have adverse reactions. Those with immunodeficiency disorders should not receive live vaccines.
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? Mentioned in ? References in periodicals archive
 
Strain variation among Bordetella permssis isolates in Finland, where the whole-cell pertussis vaccine has been used for 50 years.
Bordetella pertussis, Finland and France by Guiso, Nicole / Emerging Infectious Diseases
In 1982, for example, parents whose children were injured by the whole-cell pertussis vaccine formed the organization Dissatisfied Parents Together (DPT) and lobbied for passage of the National Childhood Vaccine Injury Act, which went into effect October 1, 1988.
Vaccinations: why all the fuss? by O'Mara, Peggy / Mothering
Nearly a century after a pertussis vaccine became available, the disease appears to be rebounding in adolescents and adults, a variety of studies shows.
Persistent cough: pertussis rises in young adults and infants by Harder, B. / Science News
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