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phagosome |
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phagosome [′fag·ə‚sōm] (cell and molecular biology) A closed intracellular vesicle containing material captured by phagocytosis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Lerner speculates that antibodies produce an extra dollop of hydrogen peroxide within the phagosome by converting this singlet oxygen into superoxide anions, just as antibodies do in the experiments where the singlet oxygen is generated by ultraviolet light. Phagosomes are competent organelles for antigen cross-presentation," describes a new mechanism for antigen presentation that occurs following association of the phagosome (an organelle involved in protein and pathogen degradation) with the endoplasmic reticulum (an organelle involved in protein synthesis and antigen presentation). Michel Desjardins, show that the origin of the phagosome membrane derives from the direct recruitment and fusion of the endoplasmic reticulum (ER) with the macrophage plasma membrane (PM). |
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