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Phenobarbital

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phenobarbital [¦fē·nō′bär·bə‚tȯl]
(pharmacology)
C12H12N2O3A crystalline compound, 5-ethyl-5-phenylbarbituric acid, with a slightly bitter taste, melting at 174-178°C; soluble in water, alcohol, chloroform, and ether; used in medicine as a long-acting sedative, anticonvulsant, and hypnotic.
Phenobarbital 

(trade name, Luminal), a medicinal preparation of the barbiturate group. Taken in powder or tablet form, phenobarbital is a long-acting soporific and is used in the treatment of such conditions as epilepsy and vascular spasms. Phenobarbital may be combined, in tablet form, with various other substances, including analgesic and spasmolytic preparations (for example, Andipal, Camphodal, or Paluphin).
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We know that early-life exposure to AEDs such as Phenobarbital triggers cell death in many brain regions associated with the onset of schizophrenia," said Guillermo Palchik, a doctoral student in the department of pediatrics at GUMC.
Epilepsy drug could raise schizophrenia risk by Asian News International
In 2008, three new drugs developed by Nobelpharma which are Nobelzin(R) capsules for the treatment of Wilson's disease, Lunabell(R) compound tablets for the treatment of dysmenorrhea associated with endometriosis, and Nobelbar(R) Intravenous Phenobarbital for the treatment of neonatal convulsion and status epilepticus successively received approval from MHLW.
Eisai and Nobelpharma Sign License Agreement for GLIADEL(R) WAFER in ... by JCN Newswires
Phenobarbital (Luminal) This drug, which is a barbiturate, has been in use in the treatment of grand mal epilepsy since 1912, and is still employed since it is inexpensive and has low toxicity.
Epileptic Disorders Medicines and Drugs by Ricky Hussey / Health, general community
 
 
 
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