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Related to phenobarbitone: phenytoin


C12H12N2O3 A crystalline compound, 5-ethyl-5-phenylbarbituric acid, with a slightly bitter taste, melting at 174-178°C; soluble in water, alcohol, chloroform, and ether; used in medicine as a long-acting sedative, anticonvulsant, and hypnotic.



(trade name, Luminal), a medicinal preparation of the barbiturate group. Taken in powder or tablet form, phenobarbital is a long-acting soporific and is used in the treatment of such conditions as epilepsy and vascular spasms. Phenobarbital may be combined, in tablet form, with various other substances, including analgesic and spasmolytic preparations (for example, Andipal, Camphodal, or Paluphin).

References in periodicals archive ?
Because not all patients on phenytoin or phenobarbitone develop gingival overgrowth, identifying patients at risk is important in order to take necessary measures to minimize the onset and severity of this condition.
While the phenobarbitone induced sleeping time test is commonly employed for the assessment of hypnotic properties.
The effect of L-arginine on the memory impairing action of phenobarbitone in rats that convulsed after the injection of picrotoxin.
However, advances in medication in the 20th century - particularly the discovery of phenobarbitone in the 1920s - meant it was largely ignored for more than 100 years.
Certain herbal remedies such as borage oil and evening primrose oil contain gamolenic acid that lowers the seizure threshold in epileptics thus counteracting drugs such as phenobarbitone and phenytoin.
Effects of valproic acid, carbamazepine, and phenobarbitone on the fatty acid composition of erythrocyte membranes in children.
Phenobarbitone tablets: circular white tablets with APS 0310, COX/PO or C/PP etched on one side
Mr Prais asked her if she remembered Helen taking barbiturate tablets - called phenobarbitone - on the night out, but Ms Hudson said she could not recall.
1985, "Application of derivative-differential UV spectrophotometry for the determination of oxazepam or phenobarbitone in the presence of dipyridamole," J.
The anticonvulsant drugs phenobarbitone and phenytoin also can contribute to osteoporosis by altering bone mineral metabolism in ways that reduce BMD.