phenylthiourea


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phenylthiourea

[¦fen·əl¦thī·ō·yu̇′rē·ə]
(organic chemistry)
C6H5NHCSNH2 A crystalline compound that has either a bitter taste or is tasteless, depending on the heredity of the taster; used in human genetics studies.
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This process can be inhibited when phenoloxidase is irreversibly deactivated by phenylthiourea (PTU), a copper chelating agent (Laskin & Piccinini 1986).
An alternative explanation may be that the 5"-hydroxyl group of 3 chelates to one or both of the copper ions within the active site cleft, similar to the previously described binding of phenylthiourea (Klabunde et al.
The DDT-R locus has become almost 'mythical' as researchers over the years associated numerous traits with it, such as susceptibility to the chemical phenylthiourea and resistance to other insecticides (organophosphates and carbamates).
Just as the ability to taste the bitter compound phenylthiourea (PTC) is inherited, anosmia--the inability of a person with otherwise normal olfactory abilities to detect a specific odor--is thought to be genetically based in some cases.
The stock solutions of the following chemicals were prepared in distilled water: 10 mM/1 dopamine (Sigma), 10 mM/I N-acetyldopamine (Sigma), 5 mM/l phenylthiourea (Sigma), 0.
15 M phosphate buffered saline (PBS) + 1 mM phenylthiourea + 1 mM ethylene-diamine-tetra acetic acid (pH 7.