Candida strains were assayed for extracellular phospholipase
activity as described previously (Yousuf et al.
Increased calcium-independent phospholipase
A2 activity in first but not in multiepisode chronic schizophrenia.
A2 activity in a marker of small, dense LDL particles in human plasma.
Snake venom phospholipases
A2 (PLA2) show myotoxic activity and also evoke inflammatory and nociceptive responses (12).
Since all isolates expressed some degree of adhesion (except for hand isolates 313 and 385), SAP, and phospholipase
B activity, these phenotypes may be necessary but not sufficient prerequisites for infection.
Lp-PLA2 is a 441-amino acid protein, encoded by the phospholipase
A2, group VII (platelet-activating factor acetylhydrolase, plasma) (PLA2G7) gene, which is produced by inflammatory cells.
A2 (Lp-PLA2) is a novel biomarker reflecting a proinflammatory state.
The presence of PCPLC and another phospholipase
enzyme (PIPLC) are required for virulence, although detection of one is sufficient for the identification of pathogenicity.
Structural and functional characterization inhibitor and hypotensive phospholipase
No difference was observed among the three serotype A strains when virulence factors such as capsule, melanin, phospholipase
activity, and ability to grow at 37[degrees]C were tested.
Aterovax's first product is a diagnostic blood test to measure activity of secretory phospholipase
A2 (sPLA2), a powerful biomarker that provides physicians with clinically relevant information about the presence of a destabilized atherosclerotic plaque.
Varespladib is a potent oral inhibitor of a number of pro-inflammatory enzymes collectively known as secretory phospholipase