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picornavirus |
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picornavirusAny of a group of the smallest known animal viruses. (Pico refers to their small size, rna to their core of RNA.) This group of spheroidal viruses includes viruses that attack the vertebrate intestinal tract and often invade the central nervous system as well (such as polioviruses), viruses that infect tissues in the vertebrate nose (rhinoviruses), and the virus agent of foot-and-mouth disease. |
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became the first to chart in atomic detail the topography of an animal virus -- human rhinovirus-14, a picornavirus that causes colds. The patent, titled Antisense Antiviral Agent and Method for Treating ssRNA Viral Infection, includes antisense compounds against RNA viruses from the picornavirus, calicivirus, togavirus and flavivirus families, where the antisense agent has an uncharged morpholino backbone supporting a targeting base sequence complementary to a viral target sequence that spans the translation initiation region of the virus. Osterhaus and others initially isolated a herpesvirus from the lungs and other organs of 8 of 35 dead seals from the afflicted areas, and a picornavirus from the lungs of 20 of 22 seals investigated. |
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picornavirus
