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Pilocarpine

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pilocarpine (pīlōkär`pēn), naturally occurring alkaloid obtained from plants of the genus Pilocarpus (family Rutaceae). By mimicking the effects of acetylcholine acetylcholine , a small organic molecule liberated at nerve endings as a neurotransmitter. It is particularly important in the stimulation of muscle tissue. The transmission of an impulse to the end of the nerve causes it to release neurotransmitter molecules onto
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, pilocarpine acts as a stimulant of the parasympathetic nervous system nervous system, network of specialized tissue that controls actions and reactions of the body and its adjustment to the environment. Virtually all members of the animal kingdom have at least a rudimentary nervous system.
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. It promotes the flow of saliva and urine and increases perspiration. Because it increases the outflow of fluid from the eye, reduces the pressure within the eye, and causes the pupil to contract, the drug is used to treat some types of glaucoma. It is also used for some tongue disorders.
pilocarpine [‚pī·lə′kär‚pēn]
(organic chemistry)
C11H16N2O2An alkaloid, in either oil or crystal form, melting at 34°C; soluble in chloroform, water, and alcohol; used in medicine.

Pilocarpine 

a cholinomimetic medicine. Pilocarpine is an alkaloid that is obtained from the plant Pilocarpus pinnatifolius, which grows mainly in Brazil. Supplied as the hydrochloride salt, it is used as an ointment or in droplet form for the treatment of certain eye diseases, including glaucoma.



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Symptoms of toxicity can develop after ingestion of 60 mg or more of jaborandi, which is equivalent to 5 to 10 mg of pilocarpine.
The pilocarpine iontophoresis and sweat-chloride quantitation method in this document is used to rule in or rule out cystic fibrosis, and is recommended by the Cystic Fibrosis Foundation.
The agency also noted the company's failure to establish and maintain procedures for identifying product during all stages of receipt, production, distribution, and installation to prevent mixups, specifically to the failure to document the correct lot numbers of the raw materials used to manufacture the Pilocarpine Interface pads, Chloride concentration test patches, and Potassium Sulfate Interface Pads, all of which were part of the CF Indicator Sweat Test System.
 
 
 
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