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pilocarpine(pīlōkär`pēn), naturally occurring alkaloid obtained from plants of the genus Pilocarpus (family Rutaceae). By mimicking the effects of acetylcholineacetylcholine
, a small organic molecule liberated at nerve endings as a neurotransmitter. It is particularly important in the stimulation of muscle tissue. The transmission of an impulse to the end of the nerve causes it to release neurotransmitter molecules onto the surface of
..... Click the link for more information. , pilocarpine acts as a stimulant of the parasympathetic nervous systemnervous system,
network of specialized tissue that controls actions and reactions of the body and its adjustment to the environment. Virtually all members of the animal kingdom have at least a rudimentary nervous system.
..... Click the link for more information. . It promotes the flow of saliva and urine and increases perspiration. Because it increases the outflow of fluid from the eye, reduces the pressure within the eye, and causes the pupil to contract, the drug is used to treat some types of glaucoma. It is also used for some tongue disorders.
a cholinomimetic medicine. Pilocarpine is an alkaloid that is obtained from the plant Pilocarpus pinnatifolius, which grows mainly in Brazil. Supplied as the hydrochloride salt, it is used as an ointment or in droplet form for the treatment of certain eye diseases, including glaucoma.