rupture

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rupture,

in medicine: see herniahernia,
protrusion of an internal organ or part of an organ through the wall of a body cavity. The hernia is enclosed by a sac formed by the lining of the cavity. It results from a weakness or rupture in the wall, usually where there is already a natural weakness.
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rupture

[′rəp·chər]
(geology)
(medicine)

rupture

Pathol
a. the breaking or tearing of a bodily structure or part
b. another word for hernia
References in periodicals archive ?
This process is accentuated by intra-plaque hemorrhage and plaque rupture with resultant thrombus formation.
If other aspects of vulnerable blood are present, such as high platelet reactivity, high blood viscosity, or others, there may be sufficient dysfunction present to result in acute thrombosis even without acute plaque rupture.
A biomarker of plaque rupture would show an increasing concentration when a (coronary) atherosclerotic plaque ruptures.
In our case, probably, he has had early onset coronary heart disease in whom the cigarette smoking was the single risk factor and cannabis smoking triggered the plaque rupture and induced thrombosis.
Some studies have shown that even in the nonallergic setting, mast cells are found in considerably higher amounts at acute plaque rupture sites than in stable organized thrombus or nonatherosclerotic coronary walls (9, 10).
Among the topics are plaque rupture models in mice, detecting and quantifying apoptosis in the vasculature, evaluating endothelial function in in-vivo microscopy, assessing protein glocoxidation in ventricular tissues, and stem cell therapy in the heart and vasculature.
Dr Cressida Lyon, from the Bristol Heart Institute, said: "This study is the first demonstration that reduction of cell death with soluble N-cadherin can reduce the likelihood of plaque rupture.
Similarly, acute, debilitating stroke, also caused in many cases by plaque rupture, often occurs without warning.
It is believed that patients with inflammatory disease, including SLE, are more likely to have vulnerable plaque rupture, accounting for more frequent events.
Plaques containing large lipid cores have been associated with plaque rupture and thrombosis in patients with coronary artery disease.
4,5) These cholesterol-independent effects include impedance or reversal of atherosclerotic plaque formation, improvements in arterial function, anti-clotting effects, anti-inflammatory effects, antioxidant effects, inhibition of smooth muscle cell proliferation during plaque formation, prevention of plaque rupture, and prevention of cardiac hypertrophy.
The leading cause of myocardial infarction in patients with coronary artery disease is plaque rupture.