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see blood clottingblood clotting,
process by which the blood coagulates to form solid masses, or clots. In minor injuries, small oval bodies called platelets, or thrombocytes, tend to collect and form plugs in blood vessel openings.
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(also thrombocyte), a formed element found in the blood of vertebrate animals and man that plays an important role in blood coagulation. The platelets of vertebrate animals (except mammals) are small ovoid cells with a solid nucleus and weakly basophilic cytoplasm. In mammals, including man, platelets are anuclear bodies 2–5 µ in diameter. The platelets normally number about 250,000–350,000 per cubic mm of blood. They have granules containing serotonin and substances involved in blood coagulation, as well as mitochondria, microtubules, glycogen granules, and sometimes ribosomes. In mammals, platelets originate in the blood-forming organs when fragments of the cytoplasm of megakaryocytes separate from the megakaryocytes. The life-span of the platelets of mammals, including man, is about five to nine days.


Markosian, A. A. Fiziologiia trombotsitov. Leningrad, 1970.


A small ice crystal which, when united with other such crystals, forms a layer of floating ice, especially sea ice, and serves as seed crystals for further thickening of the ice cover.


a minute cell occurring in the blood of vertebrates and involved in clotting of the blood
References in periodicals archive ?
In addition, macrophage-derived cytokines, platelet-derived growth factors such as platelet-derived growth factor and transforming growth factor-[beta]1, and lipid pools stimulate the proliferation and migration of adjacent smooth muscle cells, forming the intimal layer of atherosclerotic lesions.
Although hip implants are the largest market segment overall in terms of sales, the highest growth rate over the next few years in Europe is expected in advanced bone morphogenetic proteins (BMPs) and other orthobiologic agents such as allogenic-derived growth factors, blood-extracted growth factors, fibroblast growth factor, gene therapy, recombinant platelet-derived growth factors, small molecule therapies, and stem cells.
Growth factors like platelet-derived growth factor (PDGF) and stem cell factor (SCF) are naturally occurring substances capable of stimulating cellular growth, proliferation and differentiation.

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