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pleiotropic

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
pleiotropic [‚plī·ə′träp·ik]
(genetics)
Referring to a gene or mutation that has multiple effects.
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Indeed, the compounds that activate PPAR-[alpha] are pleiotropic and have been reported to exhibit a diversity of responses in addition to the hallmark effect of peroxisome proliferation, including genotoxicity (reviewed by Melnick 2001), epigenetic alterations (e.
A reexamination of the PPAR-[alpha] activation mode of action as a ... by Guyton, Kathryn Z.; Chiu, Weihsueh A.; Bateson, Thomas F.; Jinot, Jennifer; Scott, Cheryl Siegel; Br / Environmental Health Perspectives
These effects are referred to as pleiotropic effects and may influence the biology of atherosclerosis by modulating immunoregulation, inflammation, coagulation and vasomotor responsiveness independent of changes in LDLC.
A reduction in cardiovascular risk is the main aim of most ... by Rajput, M. Chiman / CME: Your SA Journal of CPD
Lipid-modifying and pleiotropic effects of gemfibrozil, simvastatin and pravastatin in patients with dyslipidemia.
Preventing vascular disease: by combating LDL oxidation and chronic ... by Goepp, Julius / Life Extension
 
 
 
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