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pleiotropic |
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pleiotropic [‚plī·ə′träp·ik] (genetics) Referring to a gene or mutation that has multiple effects. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency. IL-6 is a pleiotropic cytokine with multiple biologic activities (Van Snick 1990) that has been shown to be up-regulated after silica (Hetland et al. Mutations in the rpoB gene have been reported to confer pleiotropic phenotypes (8). |
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