podophyllin


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podophyllin

[‚päd·ə′fil·ən]
(pharmacology)
A light yellow to greenish-yellow or light brown powder with a bitter taste; soluble in alcohol, ether, and ammonium hydroxide; used in medicine. Also known as podophyllum resin.
References in periodicals archive ?
Hence, the difference obtained was statistically significant and podophyllin 20% is better treatment of genital warts than imiquimod 5%.
Podophyllin use began in the 1800s, variously as an emetic and cathartic agent to an antivenom and suicidal agent.
Lynch said vulvar warts should be treated in pregnant women, but he warned that podophyllin and its derivatives should not be used.
As with the antiviral agents and podophyllin, hairy leukoplakia often recurs several weeks after successful retinoic acid therapy.
8%) but 1% resulted in death and 1% had hypoxic ischemic sequelae secondary to podophyllin poisoning.
Podophyllin is also significant as an alterative, purgative, emetic and when given in conjunction with belladonna and Hyoscyamus it acts as a bitter tonic (Allevi et al.
Podophyllin toxicity may cause thrombocytopenia and leucopenia.
Currently many modalities like curettage cryotherapy pricking with sterile needle photodynamic therapy laser salicylic acid glycolic acid tretinoin podophyllin cantharidin trichloroacetic acid silver nitrate are available.
Podophyllum peltatum Podophyllin resin Panaxquinquefolium Ginsenosides, protopanaxadiol, commercially available for relief of colds and flu.
Propylthiouracil Goiter Same as above Thyroid USP None known None known Thyroxine None known None known TOCOLYTICS Beta- None known Tachycardia, hypothermia, sympathomimetics hypocalcemia, hypogly- cemia, hyperglycemia Indomethacin None known Oligohydramnios (>48 hours of use) Magnesium sulfate None known Hypermagnesemia, respiratory depression Nifedipine Unknown None known VACCINATIONS Influenza None known Passive immunization Pneumovaccine None known Passive immunization Tetanus toxoid None known Passive immunization VAGINAL PREPARATIONS Antifungal agents None known None known Podophyllin Mutagenesis (?
Treatments that can be done without anesthesia (cryotherapy, podophyllin, trior bichloracetic acid, and 5-fluorouracil) will lead to complete clearance in two-thirds of patients, he estimated.
Electrosurgery, excision, laser therapy (all requiring anesthesia) can have a 100% response rate, while cryotherapy, podophyllin, tri- or bichloracetic acid, and 5-fluorouracil (without anesthesia) will lead to complete clearance in two-thirds of patients.