podophyllin


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podophyllin

[‚päd·ə′fil·ən]
(pharmacology)
A light yellow to greenish-yellow or light brown powder with a bitter taste; soluble in alcohol, ether, and ammonium hydroxide; used in medicine. Also known as podophyllum resin.
References in periodicals archive ?
Role of podophyllin resin therapy in oral hairy leukoplakia in HIV infection: Clinicopathologic study.
Lozada-Nur E Podophyllin resin 25% for treatment of oral hairy leukoplakia: an old treatment for a new lesion.
Pharmacologic agents have been used in the treatment of these oral lesions with variable success; these include topical keratolytic agents such as podophyllin resin, intralesional or systemic interferon, and intralesional cidofovir injections.
Methods of treatment involve one or more of the following: cold cautery -- destroying the warts by freezing, a treatment similar to removing common warts on the hands or feet; hot cautery -- burning the warts off with an electrical instrument; laser treatment -- using a pinpoint laser light beam to burn the wart (laser surgery to the vagina is difficult and may not be successful); surgery for removal of warts, which produces scars; and treatment with chemical solutions such as Podophyllin and trichloroacetic acid, powerful drugs that destroy genital warts.
Agents administered by providers include podophyllin resin, trichioroacetic acid, and bichioroacetic acid.
The order of activity was: camptothecin paclitaxel = vinblastine < podophyllin = vincristine.
Standard treatments for anogenital warts, such as electrosurgery, cryosurgery and podophyllin applications, are all aimed at disrupting cell membranes.
Be skeptical of biopsy results suggesting vulvar intraepithelial neoplasia III if the patient was recently treated with podophyllin for condylomata, Dr.