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poliovirus vaccine

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.02 sec.
poliovirus vaccine [¦pō·lē·ō′vī·rəs vak′sēn]
(immunology)
A vaccine prepared from one or all three types of polioviruses in a live or attenuated state.


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Surveillance for untoward events demonstrated that only when large numbers of people are exposed to a vaccine or drug are adverse reactions identified (Guillain-Barre syndrome with influenza vaccines; paralysis with the Cutter poliovirus vaccine in 1955).
Oral poliovirus vaccine (OPV), a live attenuated poliovirus, interferes with the antibody response to a rotavirus vaccine.
Raul Andino of the University of California, San Francisco, and his colleagues took this poliovirus vaccine, which is live but weakened, and inserted genes that code for two crucial HIV-1 proteins.
 
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