Polycythemia Vera

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polycythemia vera [‚päl·i‚sī′thē·mē·ə ′vir·ə]

(medicine)

An absolute increase in all blood cells derived from bone marrow, especially erythrocytes.

Polycythemia Vera

(also erythremia, Vaquez’ disease), a chronic disease of the hematopoietic system first described by the French physician L. H. Vaquez in 1892. Polycythemia vera is characterized by an increase in erythrocyte, leukocyte, and platelet mass and in plasma volume. It is classified as a form of leukemia. The course of the disease is comparatively benign. The principal symptoms are a dark red coloration of the skin, elevated blood pressure, proneness to hemorrhaging and thrombosis, and enlargement of the spleen.

Cytological analysis of bone marrow is an important aid in diagnosis. Treatment includes phlebotomy and the administration of cytostatics.

REFERENCE

Vorob’ev, A. I., M. D. Brilliant. Patogenez i terapiia leikozov. Moscow, 1976.

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No references found			According to Izraeli, a similar mutation of the JAK2 in Down syndrome and leukemia causes Polycythemia Vera, a disease common in adults that leads to the overproduction of blood. New drug may help treat childhood leukemia by Asian News International The main area of focus for the JAK2 program has been the development of orally available JAK2 inhibitors to treat myeloproliferative disorders, which include myelofibrosis, polycythemia vera (PV) and essential thrombocythemia (ET). CYTOPIA APPOINTS STUDY CHAIRMAN FOR JAK2 CLINICAL TRIAL by Worldwide Biotech Although the JAK2 mutation linked to ALL differs slightly from the defect in polycythemia vera patients, research into JAK2 inhibitors already under way for that disease could speed drug development for ALL patients with Down syndrome, Izraeli says. New clue to Down syndrome, leukemia link by Science News			Polyclitus Polyclitus the Younger polyclonal polyclonal mixed cryoglobulin Polycondensation polyconic chart polyconic map projection polyconic projection Polycopidae polycrase Polycrates Polycrates' ring Polycross Polycrystal polycrystalline Polyctenidae polycyclic polycyclic aromatic hydrocarbon Polycyclic Dye polycyclic hydrocarbon polycyesis polycystic kidney polycystic ovarian syndrome polycystic ovary syndrome Polycythemia Polycythemia Vera Polydactyly Polydamas polydent Polydeuces polydipsia polydisperse colloidal system polydispersity Polydolopidae Polydore Vergil Polydorus polydymite Polyelectrolyte Polyembryony polyene polyester Polyester Adhesives Polyester Fiber polyester film polyester laminate Polyester Resin polyester rubber Polyester Varnish polyester-reinforced urethane polyestrous polyether			Polycystinea Polycystinia Polycytemia Polycytemia Polycytemia Polycythaemia Polycythaemia Polycythaemia Polycythaemia rubra vera Polycythaemia rubra vera Polycythaemia rubra vera Polycythaemia vera Polycythaemia vera Polycythaemia vera polycythemia polycythemia polycythemia polycythemia hypertonica polycythemia rubra polycythemia rubra polycythemia rubra Polycythemia rubra vera Polycythemia rubra vera Polycythemia rubra vera Polycythemia rubra vera Polycythemia rubra vera Polycythemia Rubra Vera-1 Polycythemia types Polycythemia types Polycythemia types Polycythemia Vera Polycythemia Vera Study Group Polycythemic Polycythemic Polycythemic Polycyttaria polydactyl polydactyl polydactyl polydactylia polydactylism polydactylism polydactylism polydactylous polydactylous polydactyls polydactyls polydactyls Polydactylus Polydactylus Polydactylus virginicus polydactyly polydactyly polydactyly Polydactyly and Syndactyly Polydactyly, Preaxial II polydaemonism Polydamas Polydegmon Polydegmon Polydelphis

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