polynucleotide


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polynucleotide

[¦päl·ə′nü·klē·ə‚tīd]
(biochemistry)
A linear sequence of nucleotides.
References in periodicals archive ?
The Patent covers an isolated genomic polynucleotide fragment that encodes human soluble (cytosolic) aminopeptidase P, vectors and hosts containing the fragment and fragments hybridizing to noncoding regions, as well as antisense oligonucleotides to these fragments, and methods of using these fragments to obtain human soluble aminopeptidase P to diagnose, treat, prevent and/or ameliorate a pathological disorder.
The sequential PCR amplification consisted of initial denaturation at 96degC for 1 min, 25 cycles of denaturation at 96degC for 10 s, annealing at 50-52degC for 5 s, and polynucleotide chain synthesis at 60degC for 4 min.
25 cycles of denaturation at 96C for 10 s, annealing at 50-52C for 5 s, and polynucleotide chain synthesis at 60C for 4 min.
Oocyte Factors Suppress Mitochondrial Polynucleotide Phosphorylase to Remodel the Metabolome and Enhance Reprogramming," Cell Reports, 2015; DOI: 10.
the term "isolated" differentiates claimed polynucleotides from those polynucleotides found in nature (e.
The study in Cell outlined a new role for a protein called polynucleotide phosphorylase (PNPASE) in regulating the import of RNA into mitochondria.
Mark Glover, his graduate student Zahra Havali-Shahriari and post-doctoral fellow Nicolas Coquelle solved the structure of a DNA repair enzyme called polynucleotide kinase/phosphatase, or PNKP.
The DNA chromosomes within each molecule are composed of two separate polynucleotide strands, each arranged with 23 pairs of homologous chromosomes.
XRCC1 has no catalytic activity of its own but it acts both as a scaffold and a modulator of the different activities involved in base excision repair by interacting with and bringing together DNA polymerase [beta], DNA ligase III, poly (ADP-ribose) polymerase in the N-terminal, C-terminal and central regions of XRCC1, respectively and polynucleotide kinase at the site of DNA damage (4,5).
The apparent paucity of variability has forced leprae epidemiologists to turn to the variability that is inherent in short polynucleotide repeats (VNTR) as a basis of strain typing.
6,307,039 (Method for Analyzing a Polynucleotide Containing a Variable Sequence and a Set or Array of Oligonucleotides Thereof), 6,770,751 (Method for Analyzing a Polynucleotide Containing a Variable Sequence and a Set or Array of Oligonudeotides Thereof) and 7,192,707 (Method for Analyzing Polynucleotide Targets Using Tethered Oligonucleotide Probes).
Characterization of individual polynucleotide molecules using a membrane channel.