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polyoma virus
(redirected from polyoma)

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polyoma virus

Minute infectious agent normally present in extremely small amounts in wild mice without causing obvious ill effects. It may induce cancerous tumours if grown in tissue culture and injected in large quantities into newborn mice or young hamsters, guinea pigs, and rabbits. It belongs to the Papovaviridae family of viruses.



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Viral isolation in bronchial aspirate and urine did not detect additional opportunistic viral infections such as polyoma BK virus and exogenous viral infections such as adenovirus, respiratory syncytial virus, and parainfluenzavirus in any patient.
As soon as Twarock saw the polyoma puzzle, she began seeing connections.
Hunter and colleagues use transgenic mice that develop multifocal mammary tumors to study the genetics and environmental influences on breast cancers and their metastases, These mice express the polyoma middle T gene, which causes cancer by 9 weeks and rampant metastatic disease by the time the animals are 100 days old.
 
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