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pore-forming protein

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pore-forming protein [′pȯr ‚fȯrm·iŋ ‚prō‚tēn]
(immunology)


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In theory, cells bathed in the pore-forming protein, then exposed to a specific wavelength of light might open themselves up just long enough to admit a drug before shutting back down.
Their highly toxic payload of cell death-inducing enzymes (called granzymes) and a pore-forming protein (perforin) make them one of the most potent killer cells of the human immune system.
The second NIH grant, in collaboration with the Department of Pharmaceutical Sciences at the University of Colorado Health Sciences Center, will be used to develop a novel cryopreservation method in which cells are permeabilized using a switchable, bacteria-derived, pore-forming protein.
 
 
 
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