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porphobilinogen

   Also found in: Medical, Acronyms, Wikipedia 0.04 sec.
porphobilinogen [¦pȯr·fō·bə′lin·ə·jən]
(biochemistry)
C10H14O4N2Dicarboxylic acid derived from pyrrole; a product of hemoglobin breakdown that gives the urine a Burgundy-red color.


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The ALAD gene codes for the enzyme [delta]-aminolevulinic acid dehydratase (ALAD), which catalyzes the second step of heme synthesis involving the condensation of two molecules of aminolevulinic acid (ALA) to form porphobilinogen.
[delta]-aminolevulinic acid dehydratase polymorphism and risk of ... by Inskip, Peter D. / Environmental Health Perspectives
The affinity of human erythrocyte porphobilinogen synthase for Zn2+ and Pb2+.
Blood lead is a predictor of homocysteine levels in a ... by Schwartz, Brian S. / Environmental Health Perspectives
These include aminolevulinate (ALA) dehydratase, porphobilinogen deaminase (hydroxymethylbilane synthase), and uroporphyrinogen decarboxylase in spleen and ALA synthase in liver.
Toxicogenomics of subchronic hexachlorobenzene exposure in Brown ... by Vos, Joseph G. / Environmental Health Perspectives
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