porphobilinogen


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porphobilinogen

[¦pȯr·fō·bə′lin·ə·jən]
(biochemistry)
C10H14O4N2 Dicarboxylic acid derived from pyrrole; a product of hemoglobin breakdown that gives the urine a Burgundy-red color.
References in periodicals archive ?
Fluctuations in her liver function tests, tachycardia, high blood pressure, and hyponatremia were observed during her stay in the hospital, and her 24-hour urine (total 2900 mL urine) porphobilinogen value was found to be 48.
D-aminolevulinate dehydratase (ALAD), porphobilinogen deaminase (PBGD) and magnesium chelatase (Mg-chelatase) were the key enzymes reported in the chlorophyll biosynthesis in higher plants.
Acute intermittent porphyria in Sweden: Molecular, functional and clinical consequences of some new mutations found in the porphobilinogen deaminase gene.
A qualitative urinalysis of porphobilinogen was performed, which was positive, confirming the diagnosis of acute intermittent porphyria.
Characterization of the porphobilinogen deaminase deficiency in acute intermittent porphyria.
Variegate Porphyria presents with prominent neurovisceral symptoms, urinary ALA and Porphobilinogen are increased and fluorescence emission of porphyrins here occurs at neutral pH, rather than acidic pH used in detection of congenital erythropoietic porphyria.
Porphobilinogen was found to be strongly positive in the analysis of a spot urine sample, and her uroporphyrin, corpoporphyrin and total porphyrin levels were found to be elevated in a 24-hour urine collection.
39) in a Swedish group measured the excretion of delta-aminolevulinic acid (ALA), porphobilinogen and porphyrins in patients with hepatorenal tyrosinemia who had attacks of polyneuropathy.
A random urine porphobilinogen (PBG) is a useful screening test for porphyria, although checking urine for fluorescence may be the most readily available clinical examination.
Quantitative measurement of porphobilinogen in urine by stable-isotope dilution liquid chromatography-tandem mass spectrometry.