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porphyrin

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porphyrin

Any of a class of biologically important heterocyclic compounds of a characteristic chemical structure that includes four pyrrole groups (five-membered organic rings each containing a nitrogen atom) linked by additional carbon atoms to form a large flat ring. As biological pigments, they and closely related molecules are responsible for many of the vivid colours in living organisms, where they often occur combined with metal ions and various substituents as coordination complexes (see compound). These include the magnesium-containing chlorophylls and the iron-containing heme group, a constituent (along with protein) of, e.g., hemoglobin, the cytochromes, and the enzyme catalase. In medicine, porphyrins are used in conjunction with light, often a laser beam, to induce reactions in the body against cancer and other diseases.


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tsutsugamushi DNA from blood often lacks sensitivity because some hemoglobin, iron porphyrin, and other factors may inhibit the PCR, although obtaining and processing the blood that avoids the inhibitors is possible (3,4,9).
Urinary porphyrin excretion can also be altered by exposure to xenobiotics such has PCBs (Colombi et al.
When the porphyrin molecule absorbs light, one of its electrons hops over to the buckyball.
 
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