Potentiation

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Potentiation

 

an increase in the efficiency of the physiological mechanisms after a period of activity. Potentiation is widespread in nature, but its underlying mechanisms vary from case to case.

An important part in neural activity is played by postsynaptic potentiation, manifested by facilitated transmission of a signal across a synapse for many seconds or several minutes after a period of synaptic activity. Postsynaptic potentiation is based on the increased probability of a mediator’s quanta being released from presynaptic nerve endings and is believed to be one of the mechanisms involved in learning and memory.

Potentiation is also characteristic of muscular activity (contraction potentiation) and of the sensory organs (light and sound potentiation). Here it results from the slowly subsiding effects of afterdischarge.

References in periodicals archive ?
2]-macroglobulin potentiates limulin-mediated hemolysis with the same efficiency as thiol-reacted LAM.
These results suggest that GRAPE polyphenols may potentiate vasorelaxation and reduce BP and circulating cell adhesion molecules, resulting in improvements in vascular function.
The beauty is that we are mixing FDA-approved drugs-antibiotics and iron chelators-to potentiate the effect of tobramycin on biofilm formation," said lead author Dr.
2003) suggested that a number of different dithiocarbamates potentiate the toxicity of both MPTP and paraquat in mouse models of parkinsonism.
Ribavirin may potentiate the mitochondrial toxicity of nudeoside analogues, they said.
5,21) Side effects are the result of cocaine's ability to potentiate sympathetic nerve stimulation.
Mayhew says other work by his group suggests "liposomal doxorubicin can potentiate the host defense--similar to what the people at M.
56 hectares of forest through management practices mainly honey species to facilitate their development and abundance of nectar production and other useful tools for the Apis mellifera, for activities such as arise: Potentiate the species established in the vegetation, maintaining species harvesting areas, dispersing seeds mellific interest, eliminating competition from other pioneer plants dispersed species and planting plants.
The epilepsy syndrome and valproate treatment may interact to potentiate the reproductive disturbance," she said.