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Potentiation
(redirected from potentiate)

   Also found in: Dictionary/thesaurus, Medical, Legal 0.01 sec.
Potentiation 

an increase in the efficiency of the physiological mechanisms after a period of activity. Potentiation is widespread in nature, but its underlying mechanisms vary from case to case.

An important part in neural activity is played by postsynaptic potentiation, manifested by facilitated transmission of a signal across a synapse for many seconds or several minutes after a period of synaptic activity. Postsynaptic potentiation is based on the increased probability of a mediator’s quanta being released from presynaptic nerve endings and is believed to be one of the mechanisms involved in learning and memory.

Potentiation is also characteristic of muscular activity (contraction potentiation) and of the sensory organs (light and sound potentiation). Here it results from the slowly subsiding effects of afterdischarge.



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The beauty is that we are mixing FDA-approved drugs-antibiotics and iron chelators-to potentiate the effect of tobramycin on biofilm formation," said lead author Dr.
BARCELONA -- Antidepressant use seems to potentiate the need for concomitant hypnotic medications for extended periods, despite national recommendations that the sleeping aids be prescribed for no more than 4 consecutive weeks, a large study in the United Kingdom has determined.
[FIGURE 2 OMITTED] The observations that ataxin-1 relieves repression induced by LANP (at the E4F responsive promoter), and conversely LANP potentiates ataxin-1 repression (such as those regulated by CBP) suggest that by the mutant ataxin-1/LANP interaction might cause a mixed picture of transcriptional aberrations--relieving repression on some target promoters and potentiating repression on others.
 
 
 
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