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procoagulant

   Also found in: Dictionary/thesaurus, Medical 0.04 sec.
procoagulant [¦prō·kō′ag·yə·lənt]
(biochemistry)
Any of blood clotting factors V to VIII; accelerates the conversion of prothrombin to thrombin in the presence of thromboplastin and calcium.


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This results in the release of cytokines with vasoactive and procoagulant properties (interleukins, tumor necrosis factor, platelet-activating factor, and urokinase) (17,18).
Several hypotheses have been proposed, including imbalance in autonomic systems, increases in procoagulant activities, and systemic release of inflammatory mediators (Brook et al.
Based on research in AMAA runners, an acute inflammatory response with procoagulant effects during rhabdomyolysis may play a role in triggering sudden cardiac death, analogous perhaps to acute cardiac events related to inflammation following small pox immunizations in an older population with underlying if previously undiagnosed coronary heart disease.
 
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