Progestins

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Related to progestin: progesterone

Progestins

 

gestagens, a group of substances with properties of the female sex hormone, progesterone (the hormone of the corpus luteum), and of the products of its metabolism.

Progestin are found in the corpus luteum, the placenta, ovaries, adrenals, and blood of humans and other mammals. The male sex glands also contain a certain amount of progestins. They exert influence on the mucous membrane of the uterus during pregnancy, ensuring normal development of the embryo. Substances exhibiting progestin-like activity have been obtained by chemical synthesis. Some of them (progesterone, pregnin) are used in medicine.

References in periodicals archive ?
30 /PRNewswire/ -- The first hormone replacement therapy (HRT) to combine both estrogen and progestin in a single transdermal (through the skin) patch is now available for menopausal women with an intact uterus for the relief of moderate-to-severe vasomotor symptoms such as hot flashes, night sweats and vaginal dryness.
Preliminary validation of these results will be conducted in a separate set of cases and controls from the same OS cohort, and a final validation and replication will also focus on the interactions of the disease-associated SNPs with the combined estrogen plus progestin (E+P) therapy in samples from the randomized controlled clinical trial cohort (CT).
While the risk of developing lung cancer for women using estrogen plus progestin HRT 10 years or longer was approximately 50 percent more than women not using HRT, this risk is actually quite small compared to the risk from smoking.
It pools both the estrogen only and the estrogen plus progestin data, and both groups are completely consistent--showing the same risk for probable dementia.
28) Oral desogestrel with testosterone pellets was recently found to lead to azoospermia, but requires daily administration of the progestin and a minor procedure for insertion of pellets.
The writer of the original letter, Phyllis Bronson, had caught her error about progestin and mares' urine.
One NIH study -- the Women's Health Initiative Memory Study, or WHIMS -- recently showed that taking a combination of estrogen and progestin actually increased the risk of dementia in women.
Taylor said that breast and uterine cells won't be stimulated by the estrogen plus SERM combination, so women in menopause get the benefits of estrogen without the risk of progestin.
Two types of intrauterine devices (IUD) also provide long-acting, reversible contraception in part by releasing progestin directly into the uterine lining.
Maxwell and his colleagues used the CASH data to examine the relationship between progestin and estrogen potency in combination OCPs in 434 women with endometrial cancer and 2,557 controls.
OCP users were defined as having used OCPs for at least 12 months and were divided into four cat egories by type of pill use: high estrogen and progestin; high estrogen/low progestin; low estrogen and progestin; and low estrogen high progestin.
In contrast, women who had used only regimens containing both estrogen and progestin did not have a significantly elevated risk, although data were limited for this group.

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