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Progestins
(redirected from progestin)

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Progestins 

gestagens, a group of substances with properties of the female sex hormone, progesterone (the hormone of the corpus luteum), and of the products of its metabolism.

Progestin are found in the corpus luteum, the placenta, ovaries, adrenals, and blood of humans and other mammals. The male sex glands also contain a certain amount of progestins. They exert influence on the mucous membrane of the uterus during pregnancy, ensuring normal development of the embryo. Substances exhibiting progestin-like activity have been obtained by chemical synthesis. Some of them (progesterone, pregnin) are used in medicine.



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Byline: ANI Washington, Oct 20 (ANI): A right mix of estrogen and a selective estrogen receptor modulator (SERM), which blocks the effects of estrogen in breast tissue, can significantly reduce breast cancer risk in menopausal women, say researchers Women in menopause who have symptoms are currently treated with a combination of estrogen plus progestin hormone therapy, however this treatment comes with side effects, including a higher risk of breast cancer caused by the progestin.
We also assessed risk by histologic subtype of breast cancer, by schedule of the progestin component of EPT, and by recency of use.
The results found health risks associated with estrogen plus progestin persist even a few years after stopping the drugs.
 
 
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