promyelocyte


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promyelocyte

[prō′mī·ə·lə‚sīt]
(histology)
The earliest myelocyte stage derived from the myeloblast.
References in periodicals archive ?
Two important applications of FISH are seen in the diagnosis of patients with chronic myeloid leukemia (CML) and acute promyelocyte leukemia (APL).
Peripheral blood smearshowing a leukemic promyelocyte, CLL lymphocyte, and a smudge cell (Wright-Giemsa, X 1000).
5 x 10[sup]9/L with 3% promyelocyte, 15% myelocyte, 19% metamyelocytes, 48% neutrophils, 4% lymphocytes, and 11% monocytes; and platelet count 81 x 10[sup]9/L.
They are formed at the promyelocyte stage of neutrophil development.
Maturation stages in the bone marrow are as follows: stem cell, myeloblast, promyelocyte, myelocyte, metamyelocyte, band and neutrophil.
Cinnamaldehyde induces apoptosis by ROS-mediated mitochondrial permeability transition in human promyelocyte leukemia HL-60 cells.
The HL-60 human promyelocyte leukemia cell line was kindly supplied by the Japanese Cancer Research Resource Bank (Osaka, Japan).
9 Platelets * * * Mean Platelet Volume * * * Neutrophils 7 29 58 Bands 54 50 35 Lymphocytes 10 9 5 Monocytes 7 0 2 Metamyelocyte 12 9 0 Myelocyte 8 2 0 Promyelocyte 2 1 0 Nucleated Red Blood Cells 2 0 2 Polychromasia present [dagger] [dagger] Poikilocytosis present [dagger] present Anisocytosis present [dagger] present Microcytes present [dagger] [dagger] Spherocytes present [dagger] [dagger] Mega-thrombocytes present present [dagger] Absolute Neutrophils 3.
Tissue examination showed granulocytic cells in different stages of maturation, but with a distinct and prominent shift toward immature forms at the promyelocyte and myelocyte stages.
phagocytophilum (strain USG3 propagated in HL60 promyelocyte cells), IgM and IgG antibodies to E.
Agranulocytosis with arrested maturation at the promyelocyte stage may be confused for APL; however, in agranulocytosis the patient's platelet count and hemoglobin are typically normal, the bone marrow is not hypercellular, and Auer rods are not observed.