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pronucleus |
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pronucleus [prō′nü·klē·əs] (cell and molecular biology) One of the two nuclear bodies of a newly fertilized ovum, the male pronucleus and the female pronucleus, the fusion of which results in the formation of the germinal (cleavage) nucleus. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| For example, genes contributed to the embryo via the sperm are required for placental formation: When an egg has a pronucleus from another female injected into it, no placenta develops; in contrast, an egg that has its pronucleus replaced such that all genes are paternal does not develop into a normal embryo, but the placenta develops. In Werlin's study, 75 patients undergoing PGD treatment were retrospectively reviewed to determine if embryos obtained from second day intracytoplasmic sperm injection (ICSI), single pronucleus and no pronuclei exhibited characteristics of normality and viability for transfer. |
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