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prostate specific antigen

   Also found in: Dictionary/thesaurus, Medical, Financial, Wikipedia 0.04 sec.
prostate specific antigen [¦prä‚stāt spə‚sif·ik ′ant·i·jən]
(immunology)
A glycoprotein with 240 amino acids that is expressed exclusively by human prostate epithelial cells and that exhibits protease activity; elevated levels in the blood are detected in individuals with prostate cancer. Abbreviated PSA.


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The test may offer advantages over prostate specific antigen (PSA) testing, the current standard for initial prostate cancer screening in conjunction with a digital rectal exam.
Although it would require a biopsy of prostate tissue, an HIP1 test for the cancer might be more definitive than the currently used blood test measuring the protein called prostate specific antigen, Ross says.
Induction of prostate specific antigen production by steroids and tamoxifen in breast cancer cell lines.
 
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