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protease inhibitor |
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protease inhibitor (prō`tē-ās'), any of a class of drugs that interfere with replication of the AIDS AIDS or acquired immunodeficiency syndrome, fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. ..... Click the link for more information. virus (HIV HIV (Human Immunodeficiency Virus), either of two closely related retroviruses that invade T-helper lymphocytes and are responsible for AIDS . There are two types of HIV: HIV-1 and HIV-2. HIV-1 is responsible for the vast majority of AIDS in the United States. ..... Click the link for more information. ), by blocking an enzyme (protease) necessary in the late stages of its reproduction. Clinical trials of the protease inhibitor indinavir have shown it to be especially beneficial in combination with the anti-HIV drugs AZT AZT or zidovudine (zīdō`vy ..... Click the link for more information. and 3TC, which act by blocking a different enzyme, reverse transcriptase. Saquinavir, the first member of the class to be marketed, was approved for use in 1995 by the Food and Drug Administration. |
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announced today the launch of a new drug for HIV (Human Immunodeficiency Virus) infection, HIV Protease inhibitor 'INVIRASE(R) Tablet 500 mg' (generic name: saquinavir mesilate), on September 15. In the first agreement, Medivir has outlicensed its preclinical human immunodeficiency virus (HIV) protease inhibitor project and in the second agreement provided a license for the MIV-210 polymerase inhibitor compound for HIV and hepatitis B (HBV). Have Meds, Will Travel Traveling with meds has always been a challenge for HIVers, but things got a bit easier in October when the FDA approved a tablet form of the protease inhibitor Kaletra, making one of the world's most commonly prescribed protease inhibitors travel-ready. |
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protease inhibitor
