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protein engineering

   Also found in: Wikipedia 0.01 sec.
protein engineering [′prō‚tēn ‚en·jə′nir·iŋ]
(cell and molecular biology)
The design and construction of new proteins or enzymes with novel or desired functions by modifying amino acid sequences by using recombinant deoxyribonucleic acid technology.


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The team used computational reconstruction of ancestral gene sequences, DNA synthesis, protein engineering and X-ray crystallography to resurrect and manipulate the gene for a key hormone receptor as it existed in our earliest vertebrate ancestors more than 400 million years ago.
Under the leadership of former NHS biochemist Dr Dale Athey, Orla spun out of Newcastle University in 2002, and uses protein engineering to produce applications including more accurately detecting bacteria, viruses or proteins in blood.
Khudyakov (molecular epidemiology and bioinformatics, Centers for Disease Control and Prevention) brings together 20 chapters by researchers in biotechnology and biomedicine from Europe, the US, and Mexico who also discuss genetic engineering and the development of vaccines, diagnostics, and therapeutics, and problems associated with protein engineering in these fields.
 
 
 
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