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protein kinase C

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.07 sec.
protein kinase C [¦prō‚tēn ¦kī‚nās ′sē]
(cell and molecular biology)
A Ca2+-dependent enzyme mediating the phosphorylation of certain cellular proteins, thereby regulating important physiological functions, such as cell growth, ion channel activity, secretion, and synaptic transmission. Abbreviated PKC.


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3] facilitates 3-phosphoinositide-dependent kinase-1/2 (PDK-1/2) dependent phosphorylation/activation of protein kinase B (PKB/Akt) and two atypical enzymes of the protein kinase C (PKC) family, PKC[lambda] and [zeta] (Chou et al.
Selective Protein Kinase C Activator Marks KAI's Second Clinical Program
The selective protein kinase C inhibitor Ro-32-0432, p38 MAP kinase inhibitor SB 203580, and
 
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