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proteoglycan

   Also found in: Medical, Acronyms, Wikipedia 0.01 sec.
proteoglycan [‚prōd·ē·ō′glī·kən]
(biochemistry)
A high-molecular-weight polyanionic substance covalently linked by numerous heteropolysaccharide side chains to a polypeptide chain backbone.


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They have organized the contributions into sections concentrating on glycoprotein and proteoglycan analysis; glycosylation site determination methods; the use of bioinformatic tools for analysis of mass spectrometric data on glycans; analysis of the specific single O-GlcNAc molecule found on nuclear and cytoplasmic proteins; and methods for measuring glycan biomolecular interactions using glycan arrays, mass spectrometry, nuclear magnetic resonance, antibodies, and small molecule inhibitors.
Laboratoires Serobiologiques (LS) has designed Dermican with a unique anti-aging action that targets the metabolism of a specific proteoglycan (lumican) to enhance skin firmness.
This increases the amount of inflammation and the process becomes self-perpetuating, leading to the condition known as degenerative joint disease (DJD) because the body is unable to produce enough glucosamine to generate the proteoglycan needed for repair.
 
 
 
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