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proteolysis
(redirected from proteolytic)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.02 sec.

proteolysis

Process in which a protein is broken down partially, into peptides, or completely, into amino acids, by proteolytic enzymes, present in bacteria and in plants but most abundant in animals. Proteins in food are attacked in the stomach by pepsin and in the small intestine mainly by trypsin and chymotrypsin from the pancreas. Proteolytic enzymes are secreted as zymogens, which are themselves converted by proteolysis to their active forms. Many other zymogens or precursors undergo proteolysis to form active enzymes or proteins (e.g., fibrinogen to fibrin). In cells, proteolytic degradation of old proteins is part of cellular maintenance.


proteolysis [‚prōd·ē′äl·ə·səs]
(biochemistry)
Fragmentation of a protein molecule by addition of water to the peptide bonds.


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4) It is believed that the bone erosion, periostitis, and sequestration are the results of a weakening of the bone by proteolytic enzymes within the cyst lining.
The "enzyme hypothesis" was originally developed as an explanation for why most dust mite allergens were proteolytic enzymes (principally cysteine and serine proteases, and chymotrypsin).
Proteolytic processing of sapovirus ORF1 polyprotein.
 
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