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provirus |
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provirus [prō′vī·rəs] (virology) The phage genome. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Polymerase chain reaction (PCR) and reverse transcription-PCR amplifications from proviral DNA lysates, plasma from this sample, and cells from stimulated ELISPOT wells were performed with pol primers originally used to identify the C. Starting in 1997, a number of research teams from Baltimore, San Diego, and elsewhere demonstrated that despite HAART's potent effects in limiting HIV replication, slowing the emergence of drug resistance and supporting immune reconstitution, the impact on integrated proviral DNA that existed in more than 100,000 resting but infected CD4 cells was negligible, and would not lead to viral eradication within a normal human lifespan. In contrast, the transcription factor SPI1 (spleen focus forming virus proviral integration oncogene), which is essential for the development of hematopoietic system (DeKoter and Singh 2000), is significantly upregulated in lymphocytes from study subjects with high levels of blood arsenic. |
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