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proximal convoluted tubule

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.02 sec.
proximal convoluted tubule [′präk·sə·məl ‚kän·və′lüd·əd ′tüb‚yül]
(anatomy)
The convoluted portion of the vertebrate nephron lying between Bowman's capsule and the loop of Henle; functions in the resorption of sugar, sodium and chloride ions, and water.


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These changes included minimal degeneration of some proximal convoluted tubules, apoptosis, tubular basophilia, tubular casts, increased mitotic figures, and mononuclear cellular infiltrates.
The primary target is the proximal convoluted tubule, and the damage at higher doses is irreversible (8-10).
 
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