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pruritus

   Also found in: Dictionary/thesaurus, Medical, Legal, Wikipedia, Hutchinson 0.02 sec.

itching

 or pruritus

Stimulation of nerve endings in the skin, usually incited by histamine, that evokes a desire to scratch. It is often transient and easily relieved. Pathological itching with skin changes usually signals dermatologic disease. Generalized itching without skin changes can occur in systemic diseases (e.g., metabolic and endocrine conditions, cancer, drug reactions, and kidney, blood, and liver diseases). Dry skin often itches. Treatment depends on cause.


pruritus [pru̇′rīd·əs]
(medicine)
Localized or generalized itch due to irritation of sensory nerve endings.


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It is also indicated for the symptomatic relief of pruritus and the reduction in the number of hives, and size of hives, in patients with chronic idiopathic urticaria.
TRK-820 has been developed for treatment of severe uremic pruritus in hemodialysis patients based on the agreement signed by the three parties on March 16, 2005, for joint development and marketing.
Although several histologic features are necessary to confirm a diagnosis of malignant melanoma, suspicious clinical features include asymmetry, an irregular border, a change in size or color, bleeding, ulceration, pruritus, and a diameter greater than 6 mm.
 
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