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Each animal was evaluated for stage of cuticle formation, lesion severity, depth of lesions, and presence of pseudomembranes (Smolowitz et al.
More involved cases of ischemia show geographic areas of ulceration, sometimes accompanied by pseudomembranes and marked submucosal edema.
A severe inflammatory reaction in the lamina propria with the formation of micro-ulcerations of the colonic mucosa that is covered by a pseudomembrane occurs due to the activity of the toxins (85).
Pathologist Martin Carey said the cause of death was pseudomembrane colitis - an infection that is nearly always C.
A typical C diphtheriae pseudomembrane covered the epiglottis and associated structures.
During this phase, localized areas of erosion develop a fibrinous pseudomembrane and colonization of bacteria occurs [Brown and Yoder, 2002].
Erythema follows, which may progress to ulceration and pseudomembrane formation, reaching maximum hyperalgesia and allodynia.
The mucosal surface of the small and large intestine was hemorrhagic and was covered by a pseudomembrane, suggesting ischemic enterocolitis.
The cellular composition of the pseudomembrane is varied: histiocytes are seen most often (95% of specimens), followed by giant cells (80%), and lymphocytes and plasma cells (25%).
Between 25 and 55 percent of victims, usually children under five, died either from suffocation by the pseudomembrane or effects of the toxin produced by the diphtheria bacillus.
Degranulated hemocytes develop a pseudomembrane to cover the connective tissue.
46) The histologic features of infection by these bacterial organisms are diverse and include those of acute self-limited colitis, severe acute inflammation mimicking ulcerative colitis, erosion/ulceration, and pseudomembrane formation.