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pyridoxal phosphate
(redirected from pyridoxal)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.34 sec.
pyridoxal phosphate (pĭr'ĭdŏks`əl): see coenzyme biotin, is a member of the B complex; it was first isolated in 1935 from dried egg yolk, and its structure was established in 1942. Biotin is usually found attached to a lysine residue in certain enzymes, where it participates in reactions involving the transfer of carboxyl
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; vitamin vitamin, group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes , or they form integral parts
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1 [micro]M pyridoxal phosphate (Sigma), 36 [micro]M [beta]-mercaptoethanol, and 180 [micro]M 2-amino-6,7-dimethyl-4-hydroxy5,6,7,8-tetrahydropteridine HCl (Sigma), all in a buffer of 180 mM sodium acetate and 1.
Eisenstein, Structure and Control of Pyridoxal Phosphate-Dependent Allosteric Threonine Deaminase, Structure 6 (4), 465-475 (1998).
For example, pyridoxal, better known as vitamin B6, collaborates with an enzyme that breaks down a form of starch into sugar.
 
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